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Summer Associate, Cell Culture/Upstream Process Development (Temporary)

Vir Biotechnology

Vir Biotechnology

People & HR
San Francisco, CA, USA
Posted on Saturday, April 20, 2024

Vir Biotechnology, Inc. is an immunology company focused on combining cutting-edge technologies to treat and prevent infectious diseases and other serious conditions. Vir has assembled two technology platforms that are designed to stimulate and enhance the immune system by exploiting critical observations of natural immune processes. Its current clinical development pipeline consists of product candidates targeting hepatitis B and hepatitis delta viruses and human immunodeficiency virus. Vir has several preclinical candidates in its pipeline, including those targeting influenza A and B, COVID-19, RSV/MPV and HPV.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company passionate about equality, inclusion, and respect. When everyone feels supported and encouraged to give their best, we will collectively deliver outstanding results. We are proud to be the first company to be ranked at the top of the Deloitte Fast 500 list two years in a row (2023 & 2022)!

THE OPPORTUNITY

Vir Biotechnology Inc seeks candidates who are highly self-motivated and can work in a collaborative fashion with other interdisciplinary team members in a fast-paced company that seeks to transform upstream bioprocessing. The Upstream Process Development team is responsible for the development and implementation of upstream processing methodologies of monoclonal antibodies that can be efficiently transferred to the cGMP Manufacturing Team and our CDMO partners. Additionally, the Upstream Process Development team supports other groups including Research and Development, Cell Line Development, Downstream Process Development, Manufacturing Science and Technology (MSAT), and External Manufacturing.

The primary focus of this role is to contribute to the establishment of the pilot lab for Vir’s monoclonal antibody portfolio, execute lab scale experiments to optimize platform, develop phase appropriate upstream processes, and plan, execute, and summarize bench and pilot scale production batches. Additionally, within this role, the candidate will have the opportunity to assist with pilot scale buffer preparation and follow the process through pilot downstream operations.

This is a 3 month Summer Associate position.

WHAT YOU'LL DO

  • Develop scalable processes such as mammalian (CHO) cell culture and harvest processes for upstream cell culture development.
  • Design scientifically rigorous experiments using statistical DoE where applicable and execute experiments, analyze and interpret data to further craft next studies.
  • Coordinate sourcing and ordering equipment and consumables to perform bench and pilot scale seed train and production runs.
  • Lead and implement experiments in the design, development, optimization and scale-up of protein production processes in suspension cell culture systems (shake flasks, AMBR250, bench and pilot scale bioreactors)
  • Draft standard operating procedures and master batch records for pilot scale batches and ensure all relevant information is recorded in a GLP / GDP compliant manner.
  • Summarize bench and pilot scale study results and draft experiment summary reports.
  • Potential to be cross-trained for hands-on downstream process development and pilot scale production experience.
  • Provide oral project status updates and presentations to stakeholders.
  • Align best practices and new technologies with needs of process development and manufacturing departments.
  • Work closely with Environmental Health and Safety and Quality to ensure lab work is performed in safe and compliant manner.

WHO YOU ARE AND WHAT YOU BRING

  • Currently pursuing a BS/MS/PhD in biological sciences, biochemistry, or biochemical/chemical engineering.
  • Hands-on experience with mammalian (CHO) cell culture (shake flasks, bioreactors, etc.) and aseptic laboratory techniques.
  • Understanding of general biology, biochemical engineering concepts, and biochemical pathways.
  • Observant, detail-oriented, curious, and passionate in their work.
  • Desire and ability to work collaboratively in a high paced team environment and meet deadlines.
  • Strong written and verbal communication skills, experienced in presenting data in written and verbal forms.
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WHO WE ARE AND WHAT WE OFFER

The expected salary range for this position is $23.00 to $34.00/ Hour . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Vir Biotechnology (“Vir”) is an equal opportunity employer. All employment decisions at Vir are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to race, color, religion, sex (including pregnancy), gender, gender identity, gender expression, sexual orientation, age, parental status, marital status, national origin, ancestry, disability, medical condition, genetic information (including family medical history), political affiliation, military service or any other legally protected characteristic.

This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir also strongly commits to providing employees with a work environment free of unlawful discrimination or harassment.

Vir Human Resources leads recruitment and employment for Vir. Unsolicited resumes sent to Vir from recruiters do not constitute any type of relationship between the recruiter and Vir and do not obligate Vir to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.

For hires based in the United States, Vir Biotechnology, Inc., participates in E-Verify.

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