Scientist I / II - Non Clinical
At Quell we seek to deliver truly innovative, life-changing therapies for our patients. Our vision as a company is to build a major global biopharmaceutical company bringing transformational and valued therapies for a range of autoimmune and inflammatory diseases, as well as preventing rejection in organ transplantation, based on modular engineered Tregs.
Quell Therapeutics Ltd (“Quell”), the world leader in the development of engineered T-regulatory (Treg) cell therapies for serious medical conditions driven by the immune system, announced it has raised $156 million in an oversubscribed Series B financing. The financing round was co-led by Jeito Capital, Ridgeback Capital Investments, SV Health Investors and Fidelity Management & Research Company LLC with participation from founding investor Syncona. New investors include British Patient Capital through its Future Fund: Breakthrough program, Janus Henderson Investors, Monashee Investment Management, Point72 and funds managed by Tekla Capital Management LLC
Responsibilities: (What will this person be doing day to day, what are the challenges and who will they need to work with)
Plan and execute ex vivo/in vitro experiments; take responsibility for production of cells, day-to-day monitoring of the experiment, ex vivo assessments and analysis.
· Contribute to the development of ex vivo/in vitro assays.
· Understand project goals and execute well-defined scientific projects.
· Interpret results, evaluate data and draw relevant conclusions.
· Contribute to administrative tasks associated with laboratory work.
· Draft well-organised documents (SOPs) and reports.
· Complete high-quality scientific projects requiring minimal supervision.
· Participate constructively and present data in working teams and at lab meetings.
· Plan assignments for a research group/project and troubleshoot complex problems.
· Coordinate research activities in the context of a larger group.
· Contribute to internal and external scientific literature.
· Draw relevant inferences from appropriate scientific literature and work experience.
· Provide scientific guidance and training to more junior staff.
· Represent Quell values whilst interreacting with external stakeholders.
· Comply with good lab practices and company policies.
Experience (What tasks do you want to see in candidate profiles?)
· Theoretical and practical knowledge of a variety of in vitro assays and techniques (immunological models preferred).
· Strong laboratory skills and substantial knowledge of state of the art principles and theories
· Good written and verbal communication skills
· Ability to work independently and complete research projects under supervision with moderate input
· Immunology background
· Treg, T cell or CAR-T cell experience
· Biotech experience
· Familiarity with Type I diabetes or IBD
Technical Skills (e.g - Techniques, Software, Instruments)
· In vitro primary cell culture
· Flow cytometry experience
· In vitro assay development
· In vivo experience
· Molecular biology experience
Soft Skills / Personal Qualities (e.g. - people skills, social skills, communication, attitudes, intelligence)
· Excellent organisational skills.
· A team player who is willing to be adaptable and take on new tasks to deliver on team goals.
· Good communication with both internal and external stakeholders.
· Attention to detail with good accountability and integrity.
· Reliable with a good working attitude.
· Ph.D or MD/ Ph.D in relevant scientific discipline
· Masters degree or native equivalent with 5+ years of directly related experience or;
· Bachelors degree in scientific discipline with 7 + years of relevant experience