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R&D Lab Associate

Nomic

Nomic

Montreal, QC, Canada
Posted on Friday, June 7, 2024

About us:

Nomic was founded with the purpose of making biology easier to measure. To do this, we have untangled some of the most difficult problems in protein profiling. Our team is combining DNA nanotechnology, high-dimensional flow cytometry, laboratory automation, and machine learning to develop the world’s highest throughput proteomic platform: the nELISA.

Since spinning out of McGill University, we have partnered with and provided platform access to dozens of drug discovery groups including GSK, 4 of the top 10 pharmas, and leading biotechs. We have recently launched a state of the art manufacturing and protein profiling facility that enables multiplexed measurement of >2.5M samples a year, generating an effective 500M protein assays in the process.

We are building a diverse team of engineers, scientists, and world-changers. We like to break down difficult problems using a first principles approach, often leveraging the latest breakthroughs from across the scientific and technological spectrum to drive our mission forward.

Nomic is headquartered in Montreal, Canada with a satellite research lab in Boston, Massachusetts. The majority of our team is based in Montreal and works in a new, shared office/laboratory space with an in-person, but flexible work-from-home, policy.

About the role:

Our Engineering R&D team’s mission is to de-risk and develop improvements to the nELISA platform, spanning from core DNA nanoarchitecture improvements to lab workflow improvements. As an R&D Lab Associate, you will play a critical, first-hand role in developing next-generation, highly scalable assays that drive the advancement of our nELISA platform. In particular:

  • This role will involve substantial bench work, teamwork, and attention to detail when identifying and troubleshooting errors.

  • You will collaborate with our multidisciplinary Engineering R&D and Automation teams to carry out biosensor development and to execute, and recursively optimize, large-scale experiments.

  • You will also independently plan and execute more focused R&D experiments, and work with your R&D teammates to take any insights and iterate on the design of subsequent experiments.

  • You will execute experiments that require the use of advanced liquid handlers and cytometers, as well as more common lab equipment. Using these instruments you’ll also manufacture molecular nELISA subcomponents to perform well-controlled lab experiments.

  • You’ll be an integral part of our efforts to "scale n" by contributing to the development of protocols for on-boarding protein targets to our platform that serve as fit-for-purpose proteomic assays.

  • You’ll play a major role in continuously improving our processes, including facilitating the integration of new assays into our platform, and transitioning assays from early R&D into deployable formats for our Lab Operations team will further refine and execute.

  • In addition to your day-to-day lab work, you’ll have a range of lab management responsibilities, including managing R&D inventory and transferring stocks from production, maintaining inventories of sub-builds generated during off-protocol manufacturing, and assisting with troubleshooting and maintaining R&D laboratory equipment.

What we’re looking for:

  • 3+ years of hands-on wet lab experience and a love for lab work.

  • Bachelors or Masters in a Biology, Bioengineering, or a related bioscience field, or equivalent experience in industry.

  • Knowledge of surface chemistry, sandwich immunoassays, related lab techniques such as ELISA, protein expression/purification, SDS-PAGE/western blot, cell culture, cytometry, bead-based assays, and microscopy, and proteomic tools and methods such as mass spectrometry, immunoassays, and/or separation-based techniques.

  • Experience working closely within a wet lab research and development team.

  • Excellent communication skills (verbal and written).

Join us if you:

  • Connect deeply with our mission, ambition and sense of duty. Our mission isn’t marketing flash: we developed our technology to better measure biology and discover biomarkers for early disease detection. We firmly believe we will be successful in literally eradicating certain diseases by enabling them to be diagnosed earlier. We also believe that our hard work to bring this technology to its full potential is our duty.

  • Are up for a challenge and want to grow: We are a team of problem-solvers, and we continually put ourselves to the test and go into the unknown. We have a growth mindset, both on hard and soft skills, and we rely on each other to give critical and candid feedback to ensure that we can all reach our full potential.

  • Want to be at the cutting-edge of biotechnology. The nELISA is a new tool that leverages DNA nanotechnology to generate proteomic data more efficiently than ever before. You get to design, build and run the system that will run the technology going forward.

  • Love hands-on lab work, and want to take hold of key learnings from experiments, and use them to develop improved analytical methods to ensure the robust biological validation of immunoassays.

  • Prefer working and communicating within a diverse cross-functional team. You would get to interface with teammates from the Engineering, Operations, and Commercial teams on a daily basis, joining a collaborative, diverse, and inclusive team where your ideas will be valued.

If you are passionate about lab work, want to drive innovation in proteomics, and are eager to make a meaningful impact in the world, we invite you to apply and join us on our journey to redefine proteomics and the understanding of biology.