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Principal CADD Scientist

Genesis Therapeutics

Genesis Therapeutics

Burlingame, CA, USA
Posted on Friday, November 19, 2021
Genesis Therapeutics is building a world-class computational team to accelerate drug discovery through machine learning and biophysical simulation. We are looking for computational chemists experienced in structure-based drug design to help drive rapid progress in our drug programs and play a critical role in developing our ML/MD platform.

You will

  • Work directly on multiple small molecule drug discovery programs across a varied target portfolio, including novel targets with little-to-no known chemical matter
  • Utilize off-the-shelf molecular design tools, as well as custom-built internal tools, to analyze protein-ligand structures and MD simulations
  • Work closely with our AI, software, compchem, and medchem teams to drive methods development on our ML/MD platform

You are

  • A PhD-level computational chemist with deep understanding of protein-ligand binding interactions
  • Proficient with one-or-more off-the-shelf tools for structure-based drug design, such as MOE, Pymol, and Schrodinger Suite
  • 3+ years of experience as a computational chemist / CADD scientist at pharma or biotech, using structure-based methods on active drug discovery programs

What we offer

  • The opportunity to work on high impact tools and products that are immediately deployed to accelerate the discovery of new medicines
  • Strong technical coworkers in AI, software, compchem, and medchem, who all have a powerful mix of intellectual curiosity and humility
  • Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program