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Research Associate / Sr. Research Associate - Medicinal Chemistry (m/f/d)

Dewpoint Therapeutics

Dewpoint Therapeutics

Frankfurt, Germany
Posted on Tuesday, April 25, 2023

Dewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. Together, we are leveraging a transformative shift in the understanding of cellular biology to discover and advance breakthrough therapeutics for the toughest diseases.

We are searching for a Research Associate /Sr. Research Associate of Medicinal Chemistry. You will be primarily responsible for designing and executing the synthesis of small molecules as potential active therapeutics. You will also evaluate the structure activity relationships of evolving chemical matter in order to optimize the potency, pharmacokinetics, safety, and in vivo efficacy of small molecules to become a drug. Demonstrated success in organic synthesis execution and expertise is required.

In this position you’ll be part of an energizing and supportive startup culture engaged in continuous learning, and part of an exceptional international team. This role will be based at our site in Frankfurt, Germany. Dewpoint offers great benefits, competitive salary, and amazing perks.

In this role you will...

  • Independently plan and execute multi-step synthetic sequences to obtain key target molecules, using appropriate compound purification and characterization techniques
  • Apply independent thinking to solve synthetic problems

  • Be proactive in recommending alternatives, researching new methods and techniques and seeking out others to discuss potential solutions to problems

  • Plan and select appropriate methods and techniques to perform experiments

  • Accurately analyze and record data using electronic laboratory notebooks

  • Maintain a high level of scientific integrity and safety in the laboratory

  • Participate in and present results at team meetings

  • Demonstrate good verbal communication and interpersonal skills

  • Become a valuable contributor to other initiatives as they arise in our fast paced, startup environment

To do that you will need...

  • A BS/MS with 5+ years of relevant industrial experience in synthetic organic chemistry and medicinal chemistry, or Chemielaborant/Chemo-Techniker with more than 10 years experience. Please note that PhD-level candidates will not be considered.
  • Experience in planning and execution of small and large scale multi-step synthetic sequences

  • Familiarity with modern chromatographic and analytical techniques including flash chromatography, HPLC, MSLC and NMR

  • Familiarity with ChemDraw and literature search software (e.g. SciFinder)

  • Ability to collaborate in a multidisciplinary and dynamic environment and experience in mentoring and leading scientific teams

  • Ability to communicate effectively in English, the shared language of our multicultural team

About Dewpoint

Dewpoint Therapeutics is the first company founded to apply the emerging discipline of biomolecular condensates to drug discovery. Dewpoint believes that a vast range of conditions have pathways that are regulated by condensates or arise from the dysfunction of condensates — including cancer, neurodegeneration, and metabolic disease. Dewpoint scientists are working in Boston, MA, and Dresden and Frankfurt, Germany, to translate condensate biology into treatments for the toughest diseases.

Dewpoint Therapeutics is an equal opportunity employer committed to the principles of non-discrimination in the workplace. Candidates will not be discriminated against on the basis of age, race, creed, color, religion, sex, sexual orientation, national origin, disability, marital status, or any other basis prohibited by federal, state, or local law.

Dewpoint Therapeutics has an anti-hate policy in place, along with an active staff-led Diversity, Equity, and Inclusion Committee sponsored by the CEO.

Please, no solicitations by agencies.