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Associate Scientist I/II, Biomarkers & Bioanalytics

Chroma Medicine

Chroma Medicine

Data Science
Boston, MA, USA
Posted on Saturday, November 18, 2023

Chroma Medicine is pioneering a new class of genomic medicines that harness epigenetics, nature’s innate mechanism for gene regulation, revolutionizing the treatment of genetically driven diseases. As a start-up genomic medicine company with world-leading scientific founders, strong investment backing including Newpath Partners and Atlas Venture, and experienced leadership, Chroma is positioned to be the leader in epigenetic editing.

The epigenome is nature’s gatekeeper for gene expression, governing cell phenotype and function by precisely controlling gene activity without changing the underlying DNA sequence. Building on groundbreaking research from the world’s foremost genomic medicine experts, Chroma Medicine is working at the cutting edge of precision genomics, building an entirely new class of therapeutics to achieve unparalleled control of gene expression.

We are hiring at our Boston, Massachusetts site, offering a unique opportunity to be part of our foundational Chroma team.


Chroma Medicine is in search of a motivated Associate Scientist I/II to support the development of a variety of nucleic acid and protein-based bioanalytical assays. This individual will work within a dynamic pharmacology team to develop as well as run PK/PD/biodistribution assays across multiple programs to support preclinical studies. This is a great opportunity to join an innovative biotech and directly contribute to the preclinical development process.


  • Carry out the development, optimization, and validation of biomarker assays with a focus on nucleic acid and protein (ELISA) detection and quantification.
  • Generate bioanalytical data to support multiple preclinical PK, PD, efficacy and biodistribution studies.
  • Contribute to authoring standard operating procedures, study plans, and reports.
  • Interface with vendors for sourcing of materials.
  • Communicate across multiple cross-functional teams to ensure accurate dissemination of data and other relevant information.
  • Be flexible and willing to support changing needs and goals. Do your part in supporting a healthy, supportive, solutions-focused culture.


  • Excellent analytical, problem solving and critical thinking skills
  • Strong oral and written communication skills with experience presenting scientific research
  • Excellent organizational and record-keeping abilities
  • Ability to thrive in a fast-paced, innovative, and, at times, uncertain or changing environment while remaining flexible, proactive, and resourceful
  • Adept at prioritizing and managing multiple tasks simultaneously, integrating cross-functional issues, and balancing competing priorities effectively
  • Collaborative and team-oriented mindset with a desire to positively impact a new company’s evolving culture
  • Passionate, adaptable, and keen on working in the fast-paced biotech startup space to drive cutting-edge science


  • B.S. or M.S. in biotechnology, biochemistry, cell/molecular biology, or related discipline with 6+ years of relevant laboratory experience in the pharmaceutical or biotech industry or a related academic laboratory setting
  • Strong technical expertise in bioanalytical assay development especially handling animal tissues ex-vivo, nucleic acid isolation and quantification, qPCR and/or ddPCR assay setup and operation, and a variety of ligand binding assays
  • Well-developed sterile technique and comfortable handling BL2 material
  • Strong knowledge of graphing and statistical software such as EXCEL and GraphPad Prism
  • Automation experience is a plus

Chroma Medicine is an equal opportunity employer, providing equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Chroma Medicine complies with applicable state and local laws governing nondiscrimination in employment.

COVID-19 Vaccination Policy: All Chroma Medicine team members must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemptions for medical or sincerely held religious beliefs will be considered.