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Mechanical / Materials Engineer

Cellino Biotech

Cellino Biotech

Cambridge, MA, USA
Posted on Thursday, May 18, 2023

The Company

Cellino is building a precision platform that personalizes human cells for all. Stem cell-derived regenerative medicines are poised to cure some of the toughest diseases within this decade, including Parkinson’s, diabetes, and heart disease. Patient-specific cells provide the safest, most effective cures for these indications. Currently, large scale production of stem cell therapies is challenging due to extensive manual handling, high variability, and expensive manufacturing costs. Cellino’s vision is to enable healthier lives worldwide with personalized human cells.

The Role

Cellino’s automated cell manufacturing platform is based on a closed fluidic chamber that enables uniform cell growth, high-quality imaging and precision laser cell removal using proprietary biocompatible coatings. The Engineer will focus on optimizing, characterizing and qualifying growth chamber designs, materials, fabrication, packaging and sterilization for current Good Manufacturing Practices (cGMP)-compliant clinical use. The Engineer will report to the Director of R&D, consumables.


The primary responsibility of the role is to characterize, benchmark, test and optimize the optical and biological coatings for chamber and fluidic components.

Specific responsibilities include:

  • Using a wide array of techniques to physically characterize the materials used in the growth chamber via measurement
  • Supporting the experimental work by performing thermal, optical, mechanical and fluidic modeling of the growth chamber and components.
  • Designing and performing multifactor experiments, including cell growth as well as accelerated life testing to characterize chamber and materials performance.
  • Building up internal or contract chamber and film characterization and test instrumentation, procedures, databases and analyses.
  • Producing requirements, engineering and test documentation for growth chamber and associated components.
  • Helping to qualify external manufacturing partners to transition growth chamber to production


  • Doctorate in Bioengineering, Materials Engineering, Mechanical, Chemical Engineering, Physics or other degree or experience that can aid in rapid prototyping
  • Possess a detailed and methodical approach to problem solving
  • Documenting, writing and presenting skills.

Nice-to-Have Skills and Background

  • Experience in cell culture and associated with bio techniques
  • Experience in standard cell culture assays
  • Experience in microfabrication and microfluidics
  • Programming experience (Python preferred)


  • Competitive salaries
  • Stock options
  • 401(k)
  • Employer-paid medical, dental, vision, and life insurance
  • Flexible work schedule with a minimum of 3-day in-office hybrid mode
  • Generous paid time off and sick leave + 12 company holidays
  • Parental leave

It is the policy of Cellino Biotech, Inc. to provide equal employment opportunity for all applicants and employees. The Company does not unlawfully discriminate on the basis of race, religion, creed, color, national origin, ancestry, physical and/or mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, transgender status, pregnancy, marital status, age, sexual orientation, and military or veteran status, or any other basis protected by law. It also prohibits unlawful discrimination and harassment based on the perception that anyone has any of those characteristics or is associated with a person who has or is perceived as having any of those characteristics.

Cellino does not accept unsolicited resumes from any source other than directly from potential candidates. Any resumes submitted by a staffing agency in the absence of a current executed contract will automatically become Cellino's property and no recruiting fees or other obligations will be owed in the event of a potential hiring.