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Senior Mechanical Engineer (I,II,III)



Other Engineering
South San Francisco, CA, USA
Posted on Monday, June 1, 2020
Position Summary
Cellares is seeking an innovative and highly motivated Senior Mechanical Engineer, who will contribute significantly to the development of cell therapy solutions.
The primary focus of this position will be to develop, test, and assemble critical engineering subsystems. As a Senior Mechanical Engineer, you will take ownership of a wide range of tasks pertaining to high value internal projects - from requirements capture, to CAD design and component selection, to bring-up and testing of finished assemblies. During this process, you will be required to provide in-depth analysis and help guide important decisions during design reviews and architecture discussions. You will create novel concepts through research and drive rapid feasibility studies with data collection.
This is a multidisciplinary role & this individual will interface across many parts of the company (with scientists, researchers, and engineers) to develop the best solutions possible. The successful candidate will be a resident expert in the areas of mechanical design, fluidic control, and highly automated instrument development. This is a hands-on position.
Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.


  • Responsible for the design, development, and prototyping of mechanical components & complex biotech instruments and mechanical sub-systems
  • Interface with systems & mechanical engineering teams to negotiate designs that meet product requirements & are feasible to manufacture economically
  • Work closely with Electrical, Controls, & Systems engineers on complex electromechanical designs
  • Ability to be a technical lead on complex projects that encompass electrical, mechanical, controls disciplines, and work for our internal customers
  • Conduct design reviews and present fresh ideas, new technologies and creative solutions to design problems
  • Define subsystem architecture
  • Show proof of concept through rapid prototyping. Your skills will be used to build and test your own assemblies.
  • Ability to extract design requirements from a broad spectrum of user needs
  • Identify potential design risks and provide a path to rapid derisk/pivot
  • Design and develop automated test fixtures to validate reliability and robustness of novel components
  • Work closely with the scientific team through the creation of verification /validation protocols (IQ,OQ,PQ) as well as successful execution, data generation, report and documentation


  • BS or MS in Mechanical Engineering, Mechatronics Engineering, or equivalent experience
  • 10+ years of extensive, hands-on experience in the semiconductor, biotech automation, or similar industries
  • Excellent verbal, written, presentation and interpersonal skills
  • Strong analytical and problem-solving skills
  • Prior experience with FDA regulations and ISO, cGMP, QMS standards is a plus
  • Knowledge and/or hands-on experience with machine shop tools is a plus
  • Knowledge of GD&T as well as strong proficiency with SolidWorks
  • Creative, self-motivated, flexible to work in a start up environment
  • Work history with several successful iterations of highly automated instrument design and development (non-biotech industry experience is OK)
  • Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level
  • Some experience with python, or high level scripting software languages, a plus
  • Self-awareness, integrity, authenticity, and a growth mindset
Annual Salary Range: $90,000 - $210,000
Cellares total compensation package contains competitive base salaries, highly subsidized Medical, Dental, and Vision Plans, 401(k) Matching, Free EV Charging, Onsite lunches, and Stock options. All displayed pay ranges are approximate, negotiable, and location dependent.
This is Cellares
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company’s Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories around the world to meet total patient demand for cell therapies at global scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.