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Supervisor, PCR

Adaptive Biotechnologies

Adaptive Biotechnologies

People & HR, Operations
Seattle, WA, USA
Posted on Friday, October 20, 2023

At Adaptive, we’re Powering the Age of Immune Medicine. Our goal is to harness the power of the adaptive immune system to transform the way diseases are diagnosed and treated.

As an Adapter, you’ll have the opportunity to make a difference in people’s lives. With Adaptive, you’ll create a career highlight through collaboration with bright, curious colleagues working at the apex of innovation and application.

It’s time for your next chapter. Discover your story with Adaptive.

Position Overview

The Supervisor, PCR will be responsible for day-to-day supervision of Clinical Laboratorians in a fast-paced, high production laboratory processing research and clinical diagnostic samples. Adaptive’s Clinical Production laboratory is a CLIA/CAP/NYS/FDA certified laboratory, and as such this position needs to adhere to and uphold all applicable regulatory requirements. The Supervisor, PCR will also be responsible for assisting in the daily supervision and coordinating work over a specific functional area and/or shift and works in concert with Manager, MLO of the functional area to ensure all aspects of the work are covered and ensures close communication and alignment on staff management and work.

This position also contributes to strategic leadership groups including Technical Supervisors and Clinical Laboratory Directors.

Key Responsibilities and Essential Functions

  • Obtain and/or maintain competency in Laboratory Methods, as deemed necessary by Lab Ops Management.
  • Consistently demonstrate excellent clinical judgment and integrity.
  • Provide day-to-day supervision of all Testing Personnel at Adaptive Biotechnology’s Molecular Laboratory Operation:
    • Responsible for supervision of testing personnel including scheduling (e.g. frequent communication using various formats to diverse personnel, performance management, etc).
    • Facilitate orientation for new Molecular Laboratory employees and ensures training occurs in a timely manner.
    • Ensure all personnel are competent to perform clinical patient testing and that competency is maintained per required regulations for all procedures performed by the employee.
  • Responsible for the accurate and timely performance of all laboratory procedures in support of clinical and other production sample processing in Adaptive Biotechnology’s Molecular Laboratory Operations:
    • Ensure Clinical testing is performed according to documented laboratory procedures and best practices and prioritized in order to meet or exceed TAT goals.
    • Ensure all other Production testing is completed within required timelines and per documented Work Orders, Analytical Plans or Protocols.
  • Ensure that non-conformances are appropriately documented and escalated to the Clinical Lab Director or their designee, and that appropriate remedial actions occur in order to maintain acceptable levels of analytic performance, and ensure that accurate patient test results are being generated.

Core Competencies

  • Create, maintain and modify laboratory schedule; plan for and manage time for self and team to ensure tasks and deadlines are met.
  • Understand all workflows within the laboratory, as well as exhibit familiarity with processes that impact Production Laboratory workflows.
  • Offer recommendations to improve processes and assist with implementing new methods or process improvement.
  • Exhibit sound understanding of both biological processes involved in assays, as well as technical instructions for processing samples (i.e. LIMS, instrumentation, robotics, etc) underlying procedures in assigned work area (e.g. Sample Prep, PCR, Sequencing, etc).
  • Demonstrate ability to identify when a Nonconformance, Deviation or CA/PA is necessary, and appropriately escalate issues that could impact quality or result in delay of patient testing/test results.
  • Anticipate and prevent errors from occurring; assist in pinpointing root causes of errors and identifying solutions.
  • Stand behind decisions and take accountability for decisions.
  • Provide clear and effective communication to Molecular Laboratory employees to ensure they are well informed about topics that impact their work and patient testing
  • Exhibit and influence desired professional and interpersonal conduct (e.g. laboratory culture) and bring issues to the attention of lab management when appropriate.
  • Address behavioral issues with direct reports promptly and professionally; take action to correct and/or prevent problematic team issues before they occur.
  • Display ability to communicate effectively to the team, and to teams that interact with the Production Laboratory; develop and present material at group meetings, including to present at intragroup meetings.
  • Ability to collaborate across teams while ensuring the right balance between collaboration and effective working practices.
  • Contribute to the creation of a productive and professional culture; hold other team members accountable to industry best practices.
  • Exhibit a high level of professional integrity and sound judgement particularly as it pertains to clinical sample processing and result generation; proactively obtain manager/director approval when needed

Position Requirements (Education, Experience, Other)


  • Exemplary clinical judgement.
  • Extensive molecular biology skills (e.g. DNA Extraction, Purification, PCR, qPCR, next-generation DNA sequencing) and related technical knowledge.
  • Experience with laboratory automation and demonstrated laboratory best practices.
  • Experience working with human blood, tissues and/or cells as well as proper handling of biohazard material.
  • Strong communication and interpersonal skills, ability to collaborate across teams and disciplines.
  • Demonstrated leadership.
  • Some previous supervisory or team lead experience required.
  • Education and experience:
    • Earned BS degree in a Chemical, Physical or Biological Science + 7 years of related experience
      • Related experience should include greater than four years of pertinent molecular laboratory experience subsequent to qualifying of which at least one years have been spent working in a clinical molecular laboratory meeting the definition of high-complexity.
    • OR Earned MS degree with a major in Chemical, Physical or Biological Science + 4 years of related experience
      • Related experience should include greater than two years of pertinent molecular laboratory experience of which at least one year has been spent working in a clinical molecular laboratory meeting the definition of high complexity.


  • 2+ years working at Adaptive in the Clinical production laboratory
  • ASCP(MB) certification
  • Specialized knowledge and skills: Working knowledge of laboratory terminology, equipment and supplies.
  • Self-motivated and can work independently, with minimal supervision, while also working as part of a team environment in a dynamic organization. Strong interpersonal and communication skills, both written and spoken.

Working Conditions

  • The job involves working in a laboratory handling human biological specimens. Flexibility and willingness to work more than standard hours when necessary, including nights & weekends.

Physical Requirements

  • Individuals are required to sit or stand for much of the workday and perform data entry into computer systems.


Salary Range: $70,000 - $105,000

Other compensation elements include:

  • equity grant
  • bonus eligible

Schedule: Wednesday - Saturday 6:00am - 4:30pm

Interested in this position, but don’t meet all the requirements? Adaptive is committed to building diverse, equitable, and inclusive teams across our organization. Please consider applying even if your experience doesn’t match all the qualifications; you may be the exact candidate we’re searching for!

Adaptive is not currently sponsoring candidates requiring work authorization support for this position.

Adaptive’s posted compensation information includes a base salary (or hourly rate) range and summary of other available total compensation. The base salary range represents a minimum-to-maximum salary (or hourly rate) available to candidates upon extension of offer. Base salary is thoughtfully considered upon offer and is determined through multiple evaluation checks throughout the interview process, including: a candidate’s ability to meet minimum qualifications (skills/experience/education), a candidate’s ability to thoughtfully address preferred qualifications, current market conditions, and internal pay equity. Listed base salary is exclusive of bonus, commission, equity, differential pay, benefits, and other incentives.

Adaptive's benefits at-a-glance.

If you have a disability and you believe you need a reasonable accommodation to search for a job opening or to submit an online application, please e-mail This email is created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response.

NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners who have active agreements with Adaptive. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.